Description

Epithalon (Epitalon) has long been understood to help preserve telomeres, which are the
protective end caps found on fragments of DNA (chromosomes). Telomeres protect DNA from
degradation as it is replicated during cell division (one cell splitting into two). Telomeres
themselves suffer degradation, however, and eventually become too short to be effective. At this
point, a cell will either commit cell suicide in a process called apoptosis or it will go dormant in a
process called senescence. Both processes lead to aging and eventual dysfunction and disease.
Senescence is one of the primary drivers of disease and aging.
Epitalon has been shown to activate an enzyme called telomerase, which protects and repairs
telomeres. More active telomerase means that cells age slower and remain functional longer.
The net result is that overall aging appears to be slowed down. Research in rodents indicates
that Epitalon may extend life by as much as 27% via this mechanism.
Epitalon does not only activate telomerase. As noted above, Epitalon has been shown to affect
expression for several genes through alteration of DNA structure. This process, called epigenetic
modification, is of interest to scientists because it provides the foundation for controlling gene
expression at a very fine level. Research is being conducted to learn how to harness epigenetic
technology, which could potentially allow scientists to alter everything from an individual’s eye
color to how intelligent a person is or how long someone lives.
Micro-encapsulated Epitalon has shown excellent orally bioavailability in lab research studies.
Until very recently, Sub-Q administration has been the most common means of
administering peptides this is because peptides are easily degraded by enzymes in
the gastrointestinal tract, do not cross GI cell membranes all that well, and are
generally too large for transporters in the digestive tract to deal with. As it stands,
most peptides have an oral bioavailability of less than 1%.
Over the last several decades, however, scientists have developed an arsenal of tools
that help to make peptides more orally bioavailable. These tools are not only aimed at
the delivery of peptides for medicinal purposes, but to ease administration during
research as well. After all, it is easier to administer oral peptides to most mammals
than it is to administer an injection. With appropriate formulation, some peptides can
now even be administered with food or water.